PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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testing parents for genetic disorders before they have children
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engineering fruits and vegetables that resist insects and other pests
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developing ways to identify criminals through DNA fingerprinting
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using recombinant DNA to produce human hormones from bacteria
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Detailed explanation-1: -Recombinant DNA is a technology scientists developed that made it possible to insert a human gene into the genetic material of a common bacterium. This “recombinant” micro-organism could now produce the protein encoded by the human gene. Scientists build the human insulin gene in the laboratory.
Detailed explanation-2: -This process is called recombinant technology. The bacterial DNA now contains the human insulin gene and is inserted into a bacteria. When the bacterial cells reproduce, the human insulin gene is also reproduced in the cells and produces protein by transcription and translation process.
Detailed explanation-3: -’Recombinant human insulin’ became available in large amounts by recombinant DNA technology using fermentation in microorganisms (bacteria or yeast). Recombinant insulin has a superior level of purity and consistent quality compared with semisynthetic insulin.
Detailed explanation-4: -Nowadays, recombinant human insulin is mainly produced either in E. coli or Saccharomyces cerevisiae.