PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which term is essentially the opposite of pleiotropy?
A
multiple alleles
B
polygenic inheritance
C
incomplete dominance
D
codominance
Explanation: 

Detailed explanation-1: -Polygenic inheritance is opposite to pleiotropy because pleiotropy is the phenomenon in which a single gene influences multiple phenotypes, whereas, polygenic inheritance refers to inheritance of a phenotype that is controlled by multiple genes. Polygenic traits are quantitative traits.

Detailed explanation-2: -Some people confuse pleiotropy and polygenic inheritance. The major difference between the two is that pleiotropy is when one gene affects multiple characteristics (e.g. Marfan syndrome) and polygenic inheritance is when one trait is controlled by multiple genes (e.g. skin pigmentation).

Detailed explanation-3: -PLEITROPY. Pleitropy is the opposite of polygenic inheritance, as in this case on allele influences multiple traits. One great example is sickle cell anemia, which is a disorder causing one of the proteins forming hemoglobin to misform.

Detailed explanation-4: -Pleiotropy is the regulation of multiple traits by a single gene. Polygenic inheritance refers to a trait being controlled by multiple genes. 2. Pleiotropy has 2 or more than 2 genotypic outcomes. It has a wide range of genotypic results.

Detailed explanation-5: -The ability of a gene to influence more than one trait is called pleiotropy whereas in polygenic inheritance the inheritance is influenced by a number of independent genes, each having a small and similar effect.

There is 1 question to complete.