PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Would a mutation in the DNA of a skin cell be passed on to an organism’s offspring?
A
Yes, because any change to the DNA is passed on to the offspring
B
Maybe. Sex cells only use half of the body’s genetic code. It might get the copy of a gene that wasn’t mutated.
C
No. Only mutations that occur in the gametes (sex cells) are passed on to the offspring
D
Without knowing the animal, it would be hard to tell whether or not the mutation would be passed on.
Explanation: 

Detailed explanation-1: -No. Only mutations that occur in the gametes (sex cells) are passed on to the offspring c.

Detailed explanation-2: -Mutations can result from errors in DNA replication during cell division, exposure to mutagens or a viral infection. Germline mutations (that occur in eggs and sperm) can be passed on to offspring, while somatic mutations (that occur in body cells) are not passed on.

Detailed explanation-3: -For the first time, researchers have shown that mutated cells in the skin grow to form clones that compete against each other. Many mutant clones are lost from the tissue in this competition, which resembles the selection of species that occurs in evolution.

Detailed explanation-4: -Most often, gene changes related to melanoma are acquired during a person’s lifetime and are not passed on to a person’s children (inherited). In some cases, these acquired mutations seem to happen randomly within a cell, without having a clear cause.

There is 1 question to complete.