PATHOLOGY

PATHOLOGY MCQ

HAEMOPOIETIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A 25-year-old patient presented with peripheral adenopathy, involving a single cervical lymph node. A biopsy sample investigation revealed an unclear node pattern with mixed cellular infiltration. Histologycal study under higher magnification showed numerous variants of Berezovsky-Reed-Stenberg cells, lymphocytes, necrotic area and mild diffuse fibrosis. What is the most likely diagnosis?
A
Nodular lymphoma
B
Lymphogranulomatosis
C
Burkitt’s lymphoma
D
Lymphocytic lymphoma
E
Chronic lymphatic leukemia
Explanation: 

Detailed explanation-1: -Most children with supraclavicular adenopathy, children sick with fever of one week’s duration or with weight loss for which a specific diagnosis is not readily made, and some children with fixation of the lymph node to the overlying skin should undergo early biopsy.

Detailed explanation-2: -An excisional biopsy of the cervical lymph node is the gold standard test for tissue diagnosis.

Detailed explanation-3: -Malignancies, infections, autoimmune disorders, iatrogenic, and other miscellaneous conditions are considered as the causes for cervical lymphadenopathy. Unexplained cervical lymphadenopathy is a cause of concern for physician and patient because sometimes it could be the manifestation of an underlying malignancy.

There is 1 question to complete.