PATHOLOGY

PATHOLOGY MCQ

HAEMOPOIETIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A physical examination of a 42-year-old man revealed enlarged lymph nodes. A histological investigation of a lymph node showed lymphocytes, histiocytes, reticular cells, small and big Hodgkin‘s cells, multinuclear Berezovsky-ReedSternberg cells (Sternberg-Reed cells) infiltration with solitary necrotic areas. What disease such changes characteristic for?
A
Lymphogranulomatosis
B
Chronic leucosis
C
Lymphosarcoma
D
Metastasis of carcinoma of lungs
E
Acute leucosis
Explanation: 

Detailed explanation-1: -Classic Hodgkin lymphoma The cancer cells in cHL are called Reed-Sternberg cells. These cells are usually an abnormal type of B lymphocyte. Enlarged lymph nodes in people with cHL usually have a small number of Reed-Sternberg cells with a lot of normal immune cells around them.

Detailed explanation-2: -Computed tomography (CT) scan This scan can help tell if any lymph nodes or organs in your body are enlarged. CT scans are useful for looking for lymphoma in the abdomen, pelvis, chest, head, and neck. CT-guided needle biopsy: A CT can also be used to guide a biopsy needle into a suspicious area.

Detailed explanation-3: -A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin lymphoma are classic Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma.

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