PATHOLOGY MCQ
HAEMOPOIETIC SYSTEM
Question
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Appearance of normochromic normocytic anaemia in peripheral blood film.
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Presence of macrocyte in peripheral blood film.
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It is due to haemoglobin abnormalities.
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It is caused by defect in red cell membrane.
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Detailed explanation-1: -Normocytic normochromic anemia most commonly occurs as a result of miscellaneous chronic infections and systemic diseases. Most normocytic anemias appear to be the outcome of the impaired production of RBCs.
Detailed explanation-2: -Anemia of chronic disease commonly is manifested by normocytic normochromic indices; however, microcytic hypochromic indices also can be associated with anemia of chronic disease.
Detailed explanation-3: -The anemia of chronic disease is a multifactorial anemia. Diagnosis generally requires the presence of a chronic inflammatory condition, such as infection, autoimmune disease, kidney disease, or cancer. It is characterized by a microcytic or normocytic anemia and low reticulocyte count.