PATHOLOGY

PATHOLOGY MCQ

HAEMOPOIETIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Clinical investigation of a patient revealed the enlarged lymph nodes, spleen and liver. A microscopical study of the enlarged cervical (neck) lymph node showed the blurring of its structures and absence of lymphatic follicles. All microscopical views were presented by cells with round nuclei and narrow ring of a basophilic cytoplasm. What is the most likely diagnosis?
A
Lymphogranulomatosis
B
Lymphosarcoma
C
Myeloleukemia
D
Multiple myeloma
E
Lymphatic leucosis
Explanation: 

Detailed explanation-1: -Lymphocytes initially accumulate in the bone marrow and then spread to lymph nodes and other lymphoid tissues, eventually inducing splenomegaly, hepatomegaly, and systemic symptoms such as fatigue, fever, night sweats, early satiety, and unintentional weight loss.

Detailed explanation-2: -Differential Diagnosis Malignant: If the history and physical examination are consistent, lymphadenopathy may be concerning for diagnoses like metastatic breast cancer, Kaposi sarcoma, leukemias, lymphomas, metastatic disease (i.e., gastric cancer), malignant disorders of the skin.

Detailed explanation-3: -Imaging tests for swollen nodes include: MRI scan: Magnetic resonance imaging is used to detect irregularities in the body. Your doctor may order an MRI to screen for tumors, swollen glands, and even breast cancer. CT scan: CT scans can detect enlarged nodes over the entire body.

There is 1 question to complete.