PATHOLOGY MCQ
HAEMOPOIETIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The following are features of extravascular hemolysis EXCEPT:
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Raised serum bilirubin
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Increased urine urobilinogen.
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Dark urine
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Reticulocytosis
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Explanation:
Detailed explanation-1: -Dark urine may occur in patients with intravascular hemolysis, due to hemoglobinuria; chronic intravascular hemolysis may result in iron deficiency. Tachycardia, dyspnea, angina, and weakness occur in patients with severe anemia, as cardiac function is sensitive to anoxia.
Detailed explanation-2: -Urine hemosiderin may suggest severe or intravascular hemolysis. Hemosiderin is detected in iron-stained urinary sediment in sloughed renal epithelial cells. The source of urinary hemosiderin is hemoglobinuria that occurs in severe and intravascular hemolysis.
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