PATHOLOGY

Detailed explanation-1: -In practice there is considerable variation in the lifespan of human RBC. In a normal individual with a mean RBC lifespan of 115 days, this value may vary between 70 and 140 days [1, 2].

Detailed explanation-2: -Normal human red blood cells have an average life span of about 120 days in the circulation after which they are engulfed by macrophages. This is an extremely efficient process as macrophages phagocytose about 5 million erythrocytes every second without any significant release of hemoglobin in the circulation.

Detailed explanation-3: -Red blood cells (erythrocytes) The lifespan of a red blood cell is around 120 days.

Detailed explanation-4: -Erythrocytes live up to 120 days in the circulation, after which the worn-out cells are removed by a type of myeloid phagocytic cell called a macrophage, located primarily within the bone marrow, liver, and spleen.