PATHOLOGY

Detailed explanation-1: -The presence of Heinz bodies represents damage to hemoglobin and is classically observed in G6PD deficiency, a genetic disorder that causes hemolytic anemia.

Detailed explanation-2: -Heinz bodies are denatured hemoglobin, which occurs in G6PD deficiencies and in unstable hemoglobin disorders. Abdominal ultrasound may be useful in assessing for splenomegaly and gallstones. These complications are typically limited to patients with severe chronic hemolysis.

Detailed explanation-3: -The presence of Heinz bodies on a blood smear test indicates oxidative damage to the hemoglobin in red blood cells. Conditions associated with Heinz bodies include certain blood conditions, such as thalassemia or hemolytic anemia.

Detailed explanation-4: -The peripheral smear may reveal RBCs that appear to have a blister (blister cells) or have one or more “bites” (1-micron wide) taken from the cell periphery (bite cells) and RBCs with inclusions termed Heinz bodies, which are particles of denatured hemoglobin, which can be recognized only by special stains.