PATHOLOGY

Detailed explanation-1: -Diagnosis and Tests People with thalassemia have fewer healthy red blood cells and less hemoglobin than normal. They may also have smaller-than-normal red blood cells. A reticulocyte count (a measure of young red blood cells) may indicate that your bone marrow isn’t producing enough red blood cells.

Detailed explanation-2: -Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form or inadequate amount of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen. The disorder results in large numbers of red blood cells being destroyed, which leads to anemia.

Detailed explanation-3: -Alpha-Thalassemia Carriers HbA and HbF levels are normal. Notably, in the neonatal period, a minor amount (1 to 3%) of Hb Bart’s () may sometimes be detected. °-trait is usually marked by slight anemia, slightly reduced MCV and MCH, RBC microcytosis, hypochromia, and anisopoikilocytosis.