PATHOLOGY

Detailed explanation-1: -Fibroblastic (Repair) Phase: 4 days – up to 6 weeks During this phase collagen fibers are set down in the damaged area in the form of scar tissue. This type of tissue is less tensile and weaker making it susceptible to damage if overloaded.

Detailed explanation-2: -Proliferative phase. The milestones during the proliferative phase include replacement of the provisional fibrin matrix with a new matrix of collagen fibers, proteoglycans, and fibronectin to restore the structure and function to the tissue.

Detailed explanation-3: -The proliferative phase is the third phase in the healing process and lasts 6-21 days. This phase is characterized by the presence of granulation tissue and ultimately epithelialization. Fibroblasts are a key cell in this phase.

Detailed explanation-4: -Acute Inflammatory Phase: Day 1-7. Inflammation has a bad reputation, but acute (fresh) inflammation is actually essential for tissue repair. Fibroblastic Repair/Subacute Phase: Can begin at Day 4, up to 6 weeks. Remodelling Phase: As early as 2-3 weeks, up to months or years.