PATHOLOGY

Detailed explanation-1: -Wound healing can be delayed by factors local to the wound itself, including desiccation, infection or abnormal bacterial presence, maceration, necrosis, pressure, trauma, and edema.

Detailed explanation-2: -Wound healing is classically divided into 4 stages: (A) hemostasis, (B) inflammation, (C) proliferation, and (D) remodeling. Each stage is characterized by key molecular and cellular events and is coordinated by a host of secreted factors that are recognized and released by the cells of the wounding response.

Detailed explanation-3: -Factors that can Optimise Wound Healing. Five key factors that can optimise wound healing are: Address underlying disease processes. This can include: (1) blood pressure, (2) blood glucose levels, (3) tissue perfusion, (4) oedema management, (5) reinforce medication compliance, (6) offloading, and (7) pressure relief.

Detailed explanation-4: -People who smoke cigarettes and drink alcohol are more likely to experience slower healing rates than those who don’t smoke or drink. Both habits inhibit wound healing by suppressing your body’s inflammatory response and restricting the flow of blood, oxygen, nutrients, and reparative cells to the injured area.