PATHOLOGY

Detailed explanation-1: -Remodeling or also known as maturation phase is the fourth and final phase in wound healing and lasts from 21 days up to 2 years.

Detailed explanation-2: -The second phase of wound healing is called the Inflammatory Phase. It involves phagocytic cells that release reactive oxygen species, lasting for up to seven days in acute wounds and longer in chronic wounds.

Detailed explanation-3: -The wound healing process is usually characterized as four sequential but overlapping phases: haemostasis (0–several hours after injury), inflammation (1–3 days), proliferation (4–21 days) and remodelling (21 days–1 year) [1].

Detailed explanation-4: -Also called the remodeling stage of wound healing, the maturation phase is when collagen is remodeled from type III to type I and the wound fully closes. The cells that had been used to repair the wound but which are no longer needed are removed by apoptosis, or programmed cell death.

Detailed explanation-5: -Generally speaking, it only lasts about one to three days. After this period, symptoms begin to improve. A healing crisis may last longer, sometimes for weeks or months.