PATHOLOGY MCQ
HEALING AND REPAIR
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The decrease in oxygen to a tissue or cell that may result in cell death
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Cell death that occurs due to initial trauma of an injury and lack of oxygen
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A process that occurs in the subacute phase which increases blood flow to the involved area
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A process that occurs in the maturation phase that results in strengthening of the newly formed tissue
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Detailed explanation-1: -Hypoxia is a state in which oxygen is not available in sufficient amounts at the tissue level to maintain adequate homeostasis; this can result from inadequate oxygen delivery to the tissues either due to low blood supply or low oxygen content in the blood (hypoxemia).
Detailed explanation-2: -Hypoxia diminishes ATP utilization by downregulating protein translation and the activity of the Na-K-ATPase. Hypoxia diminishes ATP production in part by lowering the activity of the electron transport chain through activation of the transcription factor hypoxia-inducible factor-1.
Detailed explanation-3: -Causes of Hypoxia. Tissue hypoxia can be caused by one of 3 general abnormalities: hypoxemia, impaired oxygen delivery to tissues, and impaired tissue oxygen extraction/utilization.