PATHOLOGY

Detailed explanation-1: -The third phase of healing consists of remodeling, which begins two to three weeks after the onset of the lesion and can last for one year or more. The core aim of the remodeling stage is to achieve the maximum tensile strength through reorganization, degradation, and resynthesis of the extracellular matrix.

Detailed explanation-2: -Remodeling Scar tissue formation characterizes the final Remodeling Phase (also known as Maturation). It may occur over months or years, depending on the initial severity of the wound, its location, and treatment methods. During this phase, the new tissue gradually becomes stronger and more flexible.

Detailed explanation-3: -Finally, the body will convert this granulation tissue into a scar; this is known as the remodelling phase. The remodelling phase is a lengthy process that can take up to 1 year to complete; during this time the scar often becomes smaller and more pale in colour.

Detailed explanation-4: -Wound healing is classically divided into 4 stages: (A) hemostasis, (B) inflammation, (C) proliferation, and (D) remodeling. Each stage is characterized by key molecular and cellular events and is coordinated by a host of secreted factors that are recognized and released by the cells of the wounding response.