PATHOLOGY

Detailed explanation-1: -The proliferative phase is characterized by the formation of granulation tissue, reepithelialization, and neovascularization. This phase can last several weeks.

Detailed explanation-2: -Secondary wound healing, or secondary intention wound healing, occurs when a wound that cannot be stitched causes a large amount of tissue loss. Doctors will leave the wound to heal naturally in these cases.

Detailed explanation-3: -Proliferative phase. The milestones during the proliferative phase include replacement of the provisional fibrin matrix with a new matrix of collagen fibers, proteoglycans, and fibronectin to restore the structure and function to the tissue.

Detailed explanation-4: -Surgical wounds healing by secondary intention are open surgical wounds that are left to heal from the base up. They are often slow to heal and are prone to infection. There is relatively little information about these wounds, their management, and which treatments offer best value for money.