PATHOLOGY

Detailed explanation-1: -Granulation tissue is an important component in the wound healing process. Wounds can heal by primary intention (wound edges approximate easily) and secondary intention (wounds edges do not approximate). Granulation tissue matrix will fill wounds that heal by second intention.

Detailed explanation-2: -Fibroblasts and endothelial cells begin proliferating to form a specialized type of tissue that is the hallmark of healing called granulation tissue.

Detailed explanation-3: -In healthy stages of wound healing, granulation tissue is pink or red and uneven in texture. Healthy granulation tissue does not bleed easily. Dark granulation tissue can be a sign of infection, ischemia, or poor perfusion.

Detailed explanation-4: -Granulating tissue: Appears red and moist. Occurs when healthy tissue is formed in the remodelling phase that is well vascularised and bleeds easily. Slough tissue: Appears yellow, brown or grey. Slough is devitalised tissue made of dead cells or debris.