PATHOLOGY MCQ
HEALING AND REPAIR
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Myocardial injury heals by scarring
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Fibrosis occurs in chronic inflammation
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Tissue remodelling involves angiogenesis
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Granulation tissues hallmark of healing
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Regeneration requires intact tissues scaffold
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Detailed explanation-1: -Scaffolds, typically made of polymeric biomaterials, provide the structural support for cell attachment and subsequent tissue development.
Detailed explanation-2: -An ideal scaffold for tissue engineering should possess the following char-acteristics: 1. It is highly biocompatible and does not elicit an immunological or clinically detectable foreign body reaction. 2. It is three-dimensional and capable of regenerating tissue and organs in their normal physiological shape.
Detailed explanation-3: -The correct statement regarding tissue repair is C) Inflammation causes capillaries to dilate and become permeable. Inflammation is the first step of tissue repair and occurs soon after the injury.
Detailed explanation-4: -One of the most critical growth factors in tissue repair is transforming growth factor beta (TGF-). This growth factor belongs to a superfamily that also includes a number of other factors with wide-ranging functions, such as bone morphogenetic proteins, activins, inhibins and Müllerian inhibiting substance.