PATHOLOGY

Detailed explanation-1: -Remodelling is the final phase of the healing process in which the granulation tissue matures into scar and tissue tensile strength is increased (Figure 23.5).

Detailed explanation-2: -Earlier authors referred to 3 phases-inflammatory, fibroblastic, and maturation, which has also been denoted as inflammatory, proliferation, and remodeling-and this is maintained by some authors.

Detailed explanation-3: -The remodeling phase is also known as maturation. During remodeling, the water content of the wound reduces, and the collagen laid down during proliferation is gradually replaced by a more stable interwoven type III collagen.

Detailed explanation-4: -The scarring is created by fibroblast proliferation, a process that begins with a reaction to the clot. To mend the damage, fibroblasts slowly form the collagen scar.