PATHOLOGY

Detailed explanation-1: -There are three distinct, sequential phases of repair leading to the formation of a fibrotic scar: (1) inflammation, (2) new tissue formation, and (3) remodeling. Inflammation occurs immediately after tissue injury.

Detailed explanation-2: -Remodeling phase – This phase can continue for six months to one year after injury. Collagen continues to increase and the tissue begins to contract with the help of fibroblasts, both of which add strength to the new tissue. Excessive collagen can cause scar tissue formation.

Detailed explanation-3: -Earlier authors referred to 3 phases-inflammatory, fibroblastic, and maturation, which has also been denoted as inflammatory, proliferation, and remodeling-and this is maintained by some authors.

Detailed explanation-4: -Stage one: Haemostasis. Blood rushes to the site of the wound and clotting occurs, stopping the bleed. Stage two: Inflammation. Once haemostasis is achieved (usually within a few minutes) cells are sent to repair the wound. Stage three: Proliferation. Stage four: Remodelling. 29-Sept-2016