PATHOLOGY

Detailed explanation-1: -A cicatrix is the scar that’s left behind on skin after a wound has healed.

Detailed explanation-2: -Fibrosis is a pathological feature of most chronic inflammatory diseases. Fibrosis, or scarring, is defined by the accumulation of excess extracellular matrix components. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body.

Detailed explanation-3: -The fibrotic scar is characterized by the deposition of extracellular matrix molecules that are otherwise scarcely expressed in the neural parenchyma such as collagens, laminins and fibronectin. These molecules are generated by stromal cells (myofibroblasts), which are normally absent from the CNS parenchyma.

Detailed explanation-4: -Scars. Also called: Cicatrix, Keloid scar.