PATHOLOGY

Detailed explanation-1: -Angiogenesis is the formation of new blood vessels. This process involves the migration, growth, and differentiation of endothelial cells, which line the inside wall of blood vessels.

Detailed explanation-2: -The basic steps of sprouting angiogenesis include enzymatic degradation of capillary basement membrane, endothelial cell (EC) proliferation, directed migration of ECs, tubulogenesis (EC tube formation), vessel fusion, vessel pruning, and pericyte stabilization.

Detailed explanation-3: -(b) Angiogenesis is the formation of new blood vessels from pre-existing vessels. During this process, endothelial cells in quiescent blood vessels are activated, resulting in a vessel “sprout.” This requires endothelial cells to proliferate, migrate and differentiate to form new vascular structures.

Detailed explanation-4: -New blood vessels can develop from the walls of existing small vessels by the outgrowth of endothelial cells, which have the capacity to form hollow capillary tubes even when isolated in culture.

Detailed explanation-5: -vasculogenesis. Angiogenesis and vasculogenesis are both medical terms that refer to the formation of new blood vessels inside of your body.