PATHOLOGY

Detailed explanation-1: -The proliferative phase is characterized by the formation of granulation tissue, reepithelialization, and neovascularization.

Detailed explanation-2: -The Proliferative phase features three distinct stages: 1) filling the wound; 2) contraction of the wound margins; and 3) covering the wound (epithelialization). During the first stage, shiny, deep red granulation tissue fills the wound bed with connective tissue, and new blood vessels are formed.

Detailed explanation-3: -Overview of Wound Healing The inflammatory phase occurs immediately following the injury and lasts approximately 6 days. The fibroblastic phase occurs at the termination of the inflammatory phase and can last up to 4 weeks. Scar maturation begins at the fourth week and can last for years.

Detailed explanation-4: -Epithelialization is defined as a process of covering denuded epithelial surface. The cellular and molecular processes involved in initiation, maintenance, and completion of epithelialization are essential for successful wound closure.

Detailed explanation-5: -Every connective tissue in the body has to go through the same processes once it has sustained some damage regardless of severity. It is widely known that there are 4 distinct but overlapping phases, Bleeding, Inflammation, Proliferation & Remodelling (Figure 1.).