PATHOLOGY

Detailed explanation-1: -Following can cause intracellular edema: Abnormal leakage of fluid from the plasma to the interstitial spaces across the capillaries. Failure of the lymphatics to return fluid from the interstitium back into the blood. Depression of the metabolic systems of the tissues.

Detailed explanation-2: -The definition of edema is a swelling due to the expansion of interstitial fluid volume in tissues or an organ. Several clinical conditions present with edema, making it a critical clinical feature for diagnostic medicine.

Detailed explanation-3: -Edema occurs when an excessive volume of fluid accumulates in the tissues, either within cells (cellular edema) or within the collagen-mucopolysaccharide matrix distributed in the interstitial spaces (interstitial edema) [14, 42, 62, 64, 87, 88, 141, 215, 247, 279].

Detailed explanation-4: -Edema can affect any part of the body. But it’s more likely to show up in the legs and feet. Medicines and pregnancy can cause edema. It also can be the result of a disease, such as congestive heart failure, kidney disease, venous insufficiency or cirrhosis of the liver.