PATHOLOGY MCQ
HEALING AND REPAIR
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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occurs when coagulated blood formed by inflammation is replaced by fibrous tissues and soft callus. As the healing continues, the soft callus is replaced with hard callus.
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is removed to access the brain underneath.
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neurosurgical procedure in which part of the skull is removed to allow a swelling brain room to expand without being squeezed.
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bony structure that forms the head in vertebrates. It supports the structures of the face and provides a protective cavity for the brain.
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Detailed explanation-1: -Recovering from a bone fracture takes time and patience. One important part of the healing process is the development of a bone callus. It develops at the site of the fracture, around 2 to 6 weeks after the bone is broken. A bone callus first starts off as soft fibrous tissue and cartilage.
Detailed explanation-2: -The Reparative Stage A soft callus (a type of soft bone) replaces the blood clot that formed in the inflammatory stage. The callus holds the bone together, but isn’t strong enough for the body part to be used.
Detailed explanation-3: -Bone production begins when the clotted blood formed by inflammation is replaced with fibrous tissue and cartilage (known as soft callus). As healing progresses, the soft callus is replaced with hard bone (known as hard callus), which is visible on x-rays several weeks after the fracture.
Detailed explanation-4: -Chronic inflammation can be highly detrimental to bone healing. In chronic inflammation, TNF and the NFB signaling pathways are continuously upregulated, resulting in the differentiation and activation of osteoclasts (6, 65–68). High and persistent TNF levels damage tissues and reduce bone volume (58).