PATHOLOGY

Detailed explanation-1: -The second phase of wound healing is called the Inflammatory Phase. It involves phagocytic cells that release reactive oxygen species, lasting for up to seven days in acute wounds and longer in chronic wounds.

Detailed explanation-2: -Phagocytosis plays a central role in the defense against invading pathogens and in tissue inflammation and the successive process of healing, where macrophages and neutrophils remove cell debris and restore tissue homeostasis (29, 30).

Detailed explanation-3: -Neutrophils can engulf and destroy bacteria and cell debris by phagocytosis. Neutrophils display the same stages of phagocytosis as macrophages but contain a combination of phagocytic receptors distinct from macrophages that allow for the recognition of certain pathogens preferentially (242).

Detailed explanation-4: -Researchers have identified several of the cellular events associated with wound healing. Platelets, neutrophils, macrophages, and fibroblasts primarily contribute to the process.