PATHOLOGY

Detailed explanation-1: -Healing begins with Hemostasis. During Phase 2, a type of white blood cells called neutrophils enter the wound to destroy bacteria and remove debris.

Detailed explanation-2: -Proliferation As inflammatory cells undergo apoptosis, wound healing progresses to the proliferation phase, which is characterized by the formation of granulation tissue, angiogenesis (blood vessel formation), wound contraction, and the process of epithelialization.

Detailed explanation-3: -The proliferative phase is the third phase in the healing process and lasts 6-21 days. This phase is characterized by the presence of granulation tissue and ultimately epithelialization.

Detailed explanation-4: -The wound healing process is usually characterized as four sequential but overlapping phases: haemostasis (0–several hours after injury), inflammation (1–3 days), proliferation (4–21 days) and remodelling (21 days–1 year) [1].

Detailed explanation-5: -The proliferative phase can be subdivided into three major processes: reepithelialization (regeneration of the epidermis), the granulation tissue formation (dermal repair), and angiogenesis (revascularization of the granulation tissue) (Gurtner et al., 2008).