PATHOLOGY

Detailed explanation-1: -Wounds generally heal in 4 to 6 weeks. Chronic wounds are those that fail to heal within this timeframe. Many factors can lead to impaired healing. The primary factors are hypoxia, bacterial colonization, ischemia, reperfusion injury, altered cellular response, and collagen synthesis defects.

Detailed explanation-2: -Wound contracture is a process that occurs throughout the healing process, commencing in the fibroblastic stage. The inflammatory phase occurs immediately following the injury and lasts approximately 6 days. The fibroblastic phase occurs at the termination of the inflammatory phase and can last up to 4 weeks.

Detailed explanation-3: -Proliferative phase – This phase begins about three days after injury and overlaps with the inflammatory phase. It involves cells called fibroblasts that help to produce new collagen, create new blood vessels, and repair the avascular epithelial tissue.

Detailed explanation-4: -Penetrating wounds. Puncture wounds. Surgical wounds and incisions. Thermal, chemical or electric burns. Bites and stings. Gunshot wounds, or other high velocity projectiles that can penetrate the body. Blunt force trauma. Abrasions. Lacerations. Skin tears.