PATHOLOGY

Detailed explanation-1: -Although each component of the conduction system is capable of generating its own impulse, the rate progressively slows as you proceed from the SA node to the Purkinje fibers . Without the SA node, the AV node would generate a heart rate of 40–60 beats per minute.

Detailed explanation-2: -Potentials recorded at various sites in the atrioventricular (A-V) conduction system indicate that conduction is continuously electrical in nature and involves no synapse-like (i.e., chemical) conduction. The region between atrium and atrioventricular node has the slowest conduction velocity (. 05 M./see.)

Detailed explanation-3: -Electrical transmission through the AV conduction system is primarily limited by the AV node, which conducts in a decremental fashion to prevent excessively rapid conduction to the ventricles. The normal AV node rarely conducts faster than 200 beats per minute and slows with aging.

Detailed explanation-4: -The Purkinje fibers have the slowest rate of signal conduction in the intrinsic conduction system of the heart.