PATHOLOGY

Detailed explanation-1: -Inflammation is a nonspecific mechanism generated by the host in response to an infectious, physical, or chemical injury with recruitment of peripheral blood leukocytes and plasma proteins to the site of injury or tissue damage.

Detailed explanation-2: -Nonspecific responses that alter the intracellular environment include fever, inflammation, and interferon. These multiple defenses function with great complexity because of their interactions with one another.

Detailed explanation-3: -At the tissue level, inflammation is characterized by redness, swelling, heat, pain, and loss of tissue function, which result from local immune, vascular and inflammatory cell responses to infection or injury [5].

Detailed explanation-4: -The innate immune system is the body’s first line of defense against germs entering the body. It responds in the same way to all germs and foreign substances, which is why it is sometimes referred to as the “nonspecific” immune system.