PATHOLOGY

Detailed explanation-1: -Hyaluronidase, which is an enzyme that breaks down hyaluronic acid, has been used in medical applications for over 60 years.

Detailed explanation-2: -Bacterial hyaluronidases, enzymes capable of breaking down hyaluronate, are produced by a number of pathogenic Gram-positive bacteria that initiate infections at the skin or mucosal surfaces.

Detailed explanation-3: -Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid (HA).

Detailed explanation-4: -Hyaluronidase regarded as one of bacterial virulence factor Hyaluronidase can aid in organisms penetration into tissues rich in hyaluronic acid such as cartilage, synovial fluid and skin so are important drug diffusion agents.