PATHOLOGY

Detailed explanation-1: -Innate, or nonspecific, immunity is the defense system with which you were born. It protects you against all antigens. Innate immunity involves barriers that keep harmful materials from entering your body. These barriers form the first line of defense in the immune response.

Detailed explanation-2: -Innate immunity at birth The non-specific immune response is characterized by phagocytic cells, such as neutrophils and macrophages (See “Parts of the Immune System”). While newborns have both of these types of cells, they are limited in quantity.

Detailed explanation-3: -Medzhitov and Janeway defined innate immunity as a system of rapid immune responses that are present from birth and not adapted or permanently heightened as a result of exposure to micro-organisms, in contrast to the responses of T and B lymphocytes in the adaptive immune system [6-8].

Detailed explanation-4: -Innate immunity is the immune system that is present when you are born. It is your body’s first line of defense against germs. It includes physical barriers, such as skin and mucous membranes, and special cells and proteins that can recognize and kill germs.

Detailed explanation-5: -Internal Defenses. When pathogens enter the body, the innate immune system responds with a variety of internal defenses. These include the inflammatory response, phagocytosis, natural killer cells, and the complement system. White blood cells in the blood and lymph recognize pathogens as foreign to the body.