PATHOLOGY

Detailed explanation-1: -C3b is best known for its opsonizing activity because when it coats the microbe, phagocytosis activity is increased.

Detailed explanation-2: -Important opsonins promoting efficient phagocytosis include antibody (IgG) molecules and complement components.

Detailed explanation-3: -The main function of immunoglobulins is to react against antigens in order to mediate their elimination. Immunoglobulins react with antigens in two different ways: Bound to B lymphocytes forming the BcR receptor, which allows their reaction with antigens in their native form.

Detailed explanation-4: -Phagocytic enhancement by antibodies is called opsonization. In a process called complement fixation, IgM and IgG in serum bind to antigens and provide docking sites onto which sequential complement proteins can bind.