PATHOLOGY

PATHOLOGY MCQ

IMMUNE RESPONSE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In heavy chains, domains (regions) consists of how many amino acids?
A
110
B
250
C
70
D
250
Explanation: 

Detailed explanation-1: -The variable region of each heavy chain is approximately 110 amino acids long and is composed of a single Ig domain.

Detailed explanation-2: -Each heavy chain’s variable region is approximately 110 amino acids long and composed of a single Ig domain.

Detailed explanation-3: -In higher vertebrates, there are two types of light chain – and – whereas heavy chains can be of five types: , , , and . The type of heavy chain defines the class of immunoglobulin: IgM, IgD, IgG, IgE and IgA, respectively.

Detailed explanation-4: -There are five main classes of heavy chain C domains. Each class defines the IgM, IgG, IgA, IgD, and IgE isotypes.

Detailed explanation-5: -There are 5 types of heavy chain constant regions in antibodies (immunoglobulin) and according to these types, they are classified into IgG, IgM, IgA, IgD, and IgE.

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