PATHOLOGY

Detailed explanation-1: -If the mother is Rh-negative, her immune system treats Rh-positive fetal cells as if they were a foreign substance. The mother’s body makes antibodies against the fetal blood cells. These antibodies may cross back through the placenta into the developing baby. They destroy the baby’s circulating red blood cells.

Detailed explanation-2: -Rh incompatibility occurs when the mother’s blood type is Rh negative and her fetus’ blood type is Rh positive. Antibodies from an Rh negative mother may enter the blood stream of her unborn Rh positive infant, damaging the red blood cells (RBCs).

Detailed explanation-3: -RhIG is given when: you’re 26 to 28 weeks pregnant, and when you deliver if your baby is Rh positive. you have certain tests, treatments, or procedures (such as amniocentesis or chorionic villous sampling) during your pregnancy.

Detailed explanation-4: -Rh-hemolytic disease develops due to the conception of an Rh-negative female with an Rh-positive fetus and can cause a broad range of symptoms in the fetus/neonate. Early diagnosis and prophylaxis are crucial in this condition, especially with known high rates of neonatal mortality if it remains undiagnosed.