PATHOLOGY

PATHOLOGY MCQ

IMMUNE RESPONSE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Influenza strains that sweep around the world often carry names such as Shanghai H1N1 or Mexico City H2N2. The viruses vary in H and N surface proteins because
A
the viruses reproduce and attack people in cities more often.
B
these viruses emerged as stray DNA from the genomes of people in these cities.
C
this is where the antibodies of immune people began to break down and the old virus was again virulent.
D
when infected people develop immunity to the present virus, strains that mutate sufficiently to be outside the range of immunity are soon spread in highly populated areas.
Explanation: 

Detailed explanation-1: -Influenza A viruses are the only influenza viruses known to cause flu pandemics (i.e., global epidemics of flu disease).

Detailed explanation-2: -But the H1N1 flu strain from the pandemic became one of the strains that cause seasonal flu. Most people with the flu get better on their own. But flu and its complications can be deadly, especially for people at high risk.

Detailed explanation-3: -There are 4 types of influenza viruses, types A, B, C and D. Influenza A and B viruses circulate and cause seasonal epidemics of disease. Influenza A viruses are further classified into subtypes according to the combinations of the hemagglutinin (HA) and the neuraminidase (NA), the proteins on the surface of the virus.

Detailed explanation-4: -What is the meaning of the numbers next to the “H” and “N” in avian influenza designations? Avian influenza (AI) viruses are classified by a combination of two groups of proteins: hemagglutinin or “H” proteins, of which there are 16 (H1 to H16), and neuraminidase or “N” proteins, of which there are nine (N1 to N9).

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