PATHOLOGY MCQ
IMMUNE RESPONSE
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 Question 
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 Once the threshold potential is reached in a neuron, which of the following occurs? 
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  the interior of the cell becomes negative 
 
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  K+ channels open 
 
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  Na+ channels close 
 
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  an action potential is generated 
 
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 Explanation: 
Detailed explanation-1: -The threshold potential opens voltage-gated sodium channels and causes a large influx of sodium ions. This phase is called the depolarization.
Detailed explanation-2: -At each node, the membrane depolarizes above the threshold voltage, and the influx of sodium ions again initiates the action potential through Nav. This pattern of node-to-node propagation, saltatory conduction, can increase the conduction velocity by more than an order of magnitude over unmyelinated axons.
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