PATHOLOGY

Detailed explanation-1: -Macrophages. Macrophage is a type of white blood cell which is a phagocyte. They are scavengers which constantly move around to remove dead cells and foreign bodies such as pathogenic microbes; this occurs by the production of compounds such as nitric oxide.

Detailed explanation-2: -Monocytes are a type of phagocyte found in the bloodstream. They circulate around the body, and when a tissue is infected or inflamed they may leave the bloodstream and enter the tissue. In the tissue they differentiate into macrophages, which form the major resident population of phagocytes in normal tissues.

Detailed explanation-3: -Macrophages are monocytes that have migrated from the bloodstream into any tissue in the body. Here they aid in phagocytosis to eliminate harmful materials such as foreign substances, cellular debris and cancer cells.

Detailed explanation-4: -Monocytes and macrophages are members of the mononuclear phagocyte system, a component of innate immunity. Monocytes are bone marrow derived leukocytes that circulate in the blood and spleen. They are characterized by their ability to recognize “danger signals” via pattern recognition receptors.