PATHOLOGY

Detailed explanation-1: -The extracellular spaces are protected by the humoral immune response, in which antibodies produced by B cells cause the destruction of extracellular microorganisms and prevent the spread of intracellular infections. The activation of B cells and their differentiation into antibody-secreting plasma cells (Fig.

Detailed explanation-2: -Humoral immunity refers to antibody production and the coinciding processes that accompany it, including: Th2 activation and cytokine production, germinal center formation and isotype switching, and affinity maturation and memory cell generation.

Detailed explanation-3: -B lymphocytes or B cells produce antibodies involved in humoral immunity. B cells are produced in the bone marrow, where the initial stages of maturation occur, and travel to the spleen for final steps of maturation into naïve mature B cells.

Detailed explanation-4: -Antigen-specific antibody production. The immunity triggered by B-cells/B-lymphocytes. Antibody production by plasma B-cells. Mediation of immunity by B-cells, T-cells, and macrophages. More items •27-Aug-2022