PATHOLOGY

Detailed explanation-1: -In lymph nodes, most T cells are located in the paracortical area, which in the mouse is found approximately 150–200 mm below the organ’s surface.

Detailed explanation-2: -A simplified drawing of a human lymph node. B cells are primarily clustered in structures called lymphoid follicles, whereas T cells are found mainly in the paracortex.

Detailed explanation-3: -The inner cortex contains mostly T-cells. The deep cortical, and medullary cords contain B-cells and plasma cells. Plasma cells live for 3 days, and make IgG type antibodies. This diagram of a lymph node shows the pathways that lymphocytes can take, in and out of the lymph node.

Detailed explanation-4: -Each lymph node is divided into two general regions, the capsule and the cortex. The capsule is an outer layer of connective tissue. Underlying the capsule is the cortex, a region containing mostly inactivated B and T lymphocytes plus numerous accessory cells such as dendritic cells and macrophages.