PATHOLOGY

Detailed explanation-1: -When there is an injury, platelets release molecules into the blood that help turn on clotting factors. One important clotting factor is fibrin, a long, thin, and sticky protein. When it is turned on, it forms a mesh to hold the platelet plug in place. This is called a fibrin clot.

Detailed explanation-2: -What is fibrin? Fibrin is an insoluble protein that plays a role in blood clotting. Fibrin collects around the wound in a mesh-like structure that strengthens the platelet plug. As this mesh dries and hardens, or coagulates, the bleeding stops and the wound then heals.

Detailed explanation-3: -fibrin, an insoluble protein that is produced in response to bleeding and is the major component of the blood clot. Fibrin is a tough protein substance that is arranged in long fibrous chains; it is formed from fibrinogen, a soluble protein that is produced by the liver and found in blood plasma.

Detailed explanation-4: -The fibrin mesh traps red blood cells and platelets and eventually forms a stable blood clot. The fibrin mesh is responsible for: Providing tensile strength. Ensuring stability of the initially loose platelet plug. Mechanically impeding blood loss at the sites of blood vessel injury.

Detailed explanation-5: -Platelet factors The proteins collagen and thrombin act at the site of the injury to induce platelets to stick together. As platelets accumulate at the site, they form a mesh that plugs the injury.