PATHOLOGY

Detailed explanation-1: -Each B cell and T cell is specific for a particular antigen. What this means is that each is able to bind to a particular molecular structure. The specificity of binding resides in a receptor for antigen: the B cell receptor (BCR) for antigen and the T cell receptor (TCR) respectively.

Detailed explanation-2: -During T cell-dependent activation, B cells absorb the antigen and then present pieces of the antigen on their surface via a major histocompatibility complex (MHC). Helper T cells can then recognize those antigens via the MHC and activate the B cells.

Detailed explanation-3: -B Cell Receptors This recognition, which is central to the functioning of the adaptive immune response, results from the presence of highly specific receptors on the surfaces of B and T cells. On B cells, these receptors contain antibodies, which are responsible for antigen binding.

Detailed explanation-4: -The T-cell receptor binds to the MHC:peptide complex.