PATHOLOGY MCQ
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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helper T cell
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mast cell
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cytotoxic T cell
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plasma cells
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Detailed explanation-1: -B cell activating factor (BAFF) is a cytokine and member of the TNF family. It is produced by a wide variety of cells (neutrophils, monocytes, macrophages, DCs, and T Cells) (49). It is essential for the maturation and survival of the B Cells since it participates in the processes of differentiation and proliferation.
Detailed explanation-2: -Dendritic cells (DCs) and macrophages in the medulla bind the antigen, and some can activate the complement pathway.
Detailed explanation-3: -APCs also secrete cytokines such as IL-12, IL-4, and IL-23, which are potent differentiation factors into the Th1, Th2, or Th17 phenotypes, respectively, of CD4+ T helper cell populations and therefore APCs regulate and direct the T cell response.
Detailed explanation-4: -Types of T-cells Helper T-cells stimulate B-cells to make antibodies and help killer cells develop. Killer T-cells or cytotoxic T-cells directly kill cells that have already been infected by a foreign invader.