PATHOLOGY MCQ
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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they are activated when presented with peptide antigens by MHC class II molecules, which are expressed on the surface of antigen-presenting cells (APCs). Once activated, they divide rapidly and secrete cytokines which regulate or assist in the active immune response.
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Helper T cells
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Killer T cells
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Natural killer cells
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B-cells
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Explanation:
Detailed explanation-1: -Cytotoxic T cells (TC) express CD8, which recognizes class I MHC proteins, whereas helper T cells (TH) express CD4, which recognizes class II MHC proteins.
Detailed explanation-2: -Virus specific cytotoxic T lymphocytes (CTL) monitor cell surface MHC class I molecules for peptides derived from viral proteins and eliminate infected cells.
Detailed explanation-3: -In contrast, MHC II molecules are only found on macrophages, dendritic cells, and B cells; they present abnormal or nonself pathogen antigens for the initial activation of T cells.
Detailed explanation-4: -Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses.
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