PATHOLOGY

PATHOLOGY MCQ

IMMUNE RESPONSE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is defensive activities based on the action of pre-committed T-lymphocytes that move into action to kill the invader or activate other parts of the immune system through the production of chemicals which directly fight (act to kill) the antigen (microbe) or regulate immune response?
A
Cell-Mediated Response
B
Humoral Response
C
Cytokine Products of Cells
D
Chemical Mediators
Explanation: 

Detailed explanation-1: -B lymphocytes, also called B cells, create a type of protein called an antibody. These antibodies bind to pathogens or to foreign substances, such as toxins, to neutralize them. For example, an antibody can bind to a virus, which prevents it from entering a normal cell and causing infection.

Detailed explanation-2: -The T lymphocytes are regulators of adaptive function, serving as primary effectors for cell-mediated immunity.

Detailed explanation-3: -Armed effector cytotoxic CD8 T cells are essential in host defense against pathogens that live in the cytosol, the commonest of which are viruses. These cytotoxic T cells can kill any cell harboring such pathogens by recognizing foreign peptides that are transported to the cell surface bound to MHC class I molecules.

Detailed explanation-4: -T cells that mature into cytotoxic or killer T cells mainly destroy pathogen-infected cells, damaged cells, and cancer cells by rupturing the cell membrane. Whereas, T cells that mature into helper T cells facilitate B cells to execute antibody-mediated immune responses.

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