PATHOLOGY

Detailed explanation-1: -B lymphocytes are the cells of the immune system that make antibodies to invading pathogens like viruses. They form memory cells that remember the same pathogen for faster antibody production in future infections.

Detailed explanation-2: -Memory B cells are generated in response to T-dependent antigens, during the GC reaction, in parallel to plasma cells (Fig. 2-5). At their exit of GCs, memory B cells acquire migration properties towards extrafollicular areas of the spleen and nodes.

Detailed explanation-3: -An antibody is a protein produced by your immune system to attack and fight off these antigens.

Detailed explanation-4: -What Are the Hallmarks of B-Cell Memory Responses? Memory B cells are generated during primary responses to T-dependent vaccines. They persist in the absence of antigens but do not produce antibodies (i.e., do not protect), unless reexposure to antigen drives their differentiation into antibody-producing plasma cells.