PATHOLOGY

Detailed explanation-1: -B cells activate humoral immunity, whereas T cells activate cell-mediated immunity. The major difference between humoral and cell-mediated immunity is that humoral immunity produces antigen-specific antibodies, whereas cell-mediated immunity does not.

Detailed explanation-2: -Primary and secondary phase responses-The adaptive humoral immune response can be divided into primary and secondary phases (figure 1). During the primary phase, naïve BCRs bind an antigen and become activated.

Detailed explanation-3: -What is the difference between humoral immunity and cell-mediated immunity? One attacks the invader with antibodies released into the blood and lymph; the other attacks infected cells that display the antigens.

Detailed explanation-4: -The cell-mediated and humoral immune responses are often described separately, but they interact closely and occur simultaneously. The humoral immune response is effective against extracellular antigens and is facilitated by antibodies made by B cells that have differentiated into plasma cells.