PATHOLOGY

Detailed explanation-1: -In humans these genes are called Human Leukocyte Antigen or HLA genes, as they were first discovered through antigenic differences between white blood cells from different individuals; in the mouse they are known as the H-2 genes. There are three class I -chain genes in humans, called HLA-A, -B, and-C.

Detailed explanation-2: -major histocompatibility complex (MHC), group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances. MHC proteins are found in all higher vertebrates. In human beings the complex is also called the human leukocyte antigen (HLA) system.

Detailed explanation-3: -Which of the following apply to the protein complex known as major histocompatability complex (MCH)?-MHC is present on every cell in the body.

Detailed explanation-4: -The major histocompatibility (MHC) class I antigen presentation pathway plays an important role in alerting the immune system to virally infected cells. MHC class I molecules are expressed on the cell surface of all nucleated cells and present peptide fragments derived from intracellular proteins.

Detailed explanation-5: -The major histocompatibility complex (MHC) is a group of genes that encode proteins on the cell surface that have an important role in immune response. Their main role is in antigen presentation where MHC molecules display peptide fragments for recognition by appropriate T-cells.