PATHOLOGY

Detailed explanation-1: -The specificity of a particular antibody, i.e. what the antibody recognises, is determined by the shape of its variable region (Figure 1); a particular antibody will bind to a protein that has a region with a complementary structure to the antibody’s own variable region.

Detailed explanation-2: -An antigenic determinant is the site of an antigen molecule that is termed an epitope and interacts with the specific antigen-binding site in the variable region of an antibody molecule known as a paratope.

Detailed explanation-3: -By contrast, the class, and thus the effector function, of an antibody, is defined by the structure of its heavy chain.

Detailed explanation-4: -An immunogen is an antigen that is able to evoke an immune response, including production of antibody via the humoral response. All immunogens are antigens, but not all antigens are immunogens.